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ާ#=8~F~|{B/D_{9Ӷw3 1ML[L}g4vGjXtn~/aÏ9–r#~ pÕ5kآ~ aS`/ww9ƗB{yKИB@K8`c`{8j<ĸHQ GjX8s#Q[8Dž[9 (P؎% (F- A`Y/@y%DF endstream endobj 188 0 obj <>stream h옽7_o) PDBA#'ンG maݽflVjNѴEmZn^q8Yq5 q؛۬h͵*z -{lZW-GTM=+,~<x3 {-z[Y5j+ faW}P!֨ka>DaՇIjc}h&|: u&=~m\W?z~?>~g_My5Qc<u⼚.&q,xNq51/&YG8&q\EuN"uA)x < o? =K|X '}Qyjs=yXc>?_.7¿=u> +x/;' ,|:q-߼ endstream endobj 189 0 obj <> endobj 190 0 obj <> endobj 191 0 obj <>stream application/pdf Lowering Pathologic TNF Levels Exclusively Withinthe Brain Rapidly Alleviates Long-Standing Injury-Induced Neural Pathologies Copyright: © 2017 Spengler RN, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. It is well known that injuries to the brain can result in a decreased quality of life, waning interactions with others, and overall patient disability, even to the point of not being able to perform one’s daily living activities. Along with other pathologies, a primary component to traumatic brain injury (TBI) is chronic debilitating pain, termed neuropathic pain. Boron Neutron capture therapy BNCT History Clinical studies Sweet Robert N Spengler1 and Tracey A Ignatowski2 3* 2018-02-06T11:27:58+05:30 2018-02-06T11:27:59+05:30 2018-02-06T11:27:59+05:30 5 Adobe InDesign CS6 (Windows) uuid:a3b44e90-4bfd-443e-8244-7174d80fb0d5 xmp.did:FE00469DB0C7E411AEB789ACBE3823B3 xmp.id:F67C9E55010BE811BEA2F4AFF441BFC0 proof:pdf xmp.iid:F57C9E55010BE811BEA2F4AFF441BFC0 xmp.did:24EDAEA39FC8E411BB3BED99DE70EEB1 xmp.did:FE00469DB0C7E411AEB789ACBE3823B3 default converted from application/x-indesign to application/pdf Adobe InDesign CS6 (Windows) / 2018-02-06T11:27:58+05:30 Citation: Spengler RN and Ignatowski TA (2017)Lowering Pathologic TNF Levels Exclusively Withinthe Brain Rapidly Alleviates Long-Standing Injury-Induced Neural Pathologies. J Neurol Neurobiol3(3): doi http://dx.doi.org/10.16966/2379-7150.e111 Tracey A Ignatowski, Department of Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The StateUniversity of New York, New York, USA, Tel: (716) 829-3102; E-mail: tai1@buffalo.edu Adobe PDF Library 10.0.1 False endstream endobj 192 0 obj <> endobj xref 0 727 0000000000 65535 f 0000166334 00000 n 0000166768 00000 n 0000166792 00000 n 0000176946 00000 n 0000177029 00000 n 0000180541 00000 n 0000180858 00000 n 0000181260 00000 n 0000181319 00000 n 0000181744 00000 n 0000182321 00000 n 0000182457 00000 n 0000188249 00000 n 0000188318 00000 n 0000188418 00000 n 0000216497 00000 n 0000216757 00000 n 0000217200 00000 n 0000217225 00000 n 0000217799 00000 n 0000217885 00000 n 0000217945 00000 n 0000218331 00000 n 0000222586 00000 n 0000222623 00000 n 0000222749 00000 n 0000222900 00000 n 0000222977 00000 n 0000223339 00000 n 0000223676 00000 n 0000224286 00000 n 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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. It is well known that injuries to the brain can result in a decreased quality of life, waning interactions with others, and overall patient disability, even to the point of not being able to perform one’s daily living activities. Along with other pathologies, a primary component to traumatic brain injury (TBI) is chronic debilitating pain, termed neuropathic pain. Boron Neutron capture therapy BNCT History Clinical studies Sweet Robert N Spengler1 and Tracey A Ignatowski2 3* 2018-02-06T11:27:58+05:30 2018-02-06T11:28:03+05:30 2018-02-06T11:28:03+05:30 5 Adobe InDesign CS6 (Windows) uuid:c2880c85-a40b-412f-ad63-9ca72aaea1e1 xmp.did:FE00469DB0C7E411AEB789ACBE3823B3 xmp.id:F67C9E55010BE811BEA2F4AFF441BFC0 proof:pdf xmp.iid:F57C9E55010BE811BEA2F4AFF441BFC0 xmp.did:24EDAEA39FC8E411BB3BED99DE70EEB1 xmp.did:FE00469DB0C7E411AEB789ACBE3823B3 default converted from application/x-indesign to application/pdf Adobe InDesign CS6 (Windows) / 2018-02-06T11:27:58+05:30 Citation: Spengler RN and Ignatowski TA (2017)Lowering Pathologic TNF Levels Exclusively Withinthe Brain Rapidly Alleviates Long-Standing Injury-Induced Neural Pathologies. J Neurol Neurobiol3(3): doi http://dx.doi.org/10.16966/2379-7150.e111 Tracey A Ignatowski, Department of Pathology and Anatomical Sciences, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The StateUniversity of New York, New York, USA, Tel: (716) 829-3102; E-mail: tai1@buffalo.edu Adobe PDF Library 10.0.1 False endstream endobj 192 0 obj <> endobj 728 0 obj <>/Metadata 191 0 R/Names 729 0 R/Outlines 176 0 R/PageMode/UseOutlines/Pages 190 0 R/StructTreeRoot 193 0 R/Type/Catalog/ViewerPreferences<>>> endobj xref 0 1 0000000000 65535 f 191 2 0000290029 00000 n 0000297166 00000 n 728 1 0000297917 00000 n trailer <<0FA42BA72A925E4195A0EF08D959E28D>]/Prev 116>> startxref 298119 %%EOF